Research Report on China's Antithrombotic Drug Market, 2013-2017

(CRI-report) -Thrombosis refers to the formation of local blood clots. Among it, artery thrombosis can cause myocardial infarction, stroke, acute coronary syndrome, peripheral arterial diseases, etc.; venous thrombosis can cause pulmonary embolism. Arteriovenous thrombosis is the primary reason for incidence and death of cardiovascular diseases, which is also one of the important causes for death of cancer patients.

Nowadays, cardiac-cerebral thrombotic diseases (stroke and myocardial infarction) are severely threatening the life and health of the elderly worldwide. Cardiac-cerebral thrombotic diseases are called as the No.1 killer of the life and health of human beings currently. Cardiac-cerebral thrombotic diseases are characterized by high incidence rate, mortality rate and disability rate as well as suddenness. Since the reform and opening up, because of the continuous improvement in people’s living standards as well as the rise in aging trend, the incidence rate of cardiac-cerebral thrombotic diseases continuously rises in China. According to statistics, the proportion of people dying from cardiac-cerebral thrombotic diseases already exceeds 70% in the dead aged above 60 in China’s large cities. At present, the morbidity and mortality rates of cardiac-cerebral thrombotic diseases in China are higher than that in some developed countries. In addition, patients tend to be increasingly young.

It is reported that at present, over 7 million patients suffer from acute cardiac-cerebral thrombotic diseases (stroke and myocardial infarction) in China annually. Among them, nearly half of the patients die; in survival patients, nearly two-thirds of them are maimed or completely lose self-care ability of daily living. Cardiac-cerebral thrombotic diseases cause not only pain to patients but also huge economic burdens to their families.

Antithrombotic drugs are used for the prevention and treatment of thromboembolic diseases, with the emphasis on prevention. Clinically, they are mainly used for the treatment and prevention of acute myocardial infarction and stroke embolism, which can reduce rates of re-infarction and mortality; they can be used for the prevention of heart valve replacement surgery postoperative thrombosis and the treatment of occlusive peripheral vascular diseases, intermittent claudication, unstable angina pectoris, etc. At present, the fast-growing indication is the prevention of deep vein thrombosis after orthopedic surgeries (such as knee and hip replacement surgeries as well as abdominal surgery).

Antithrombotic drugs are divided into anticoagulants, anti-platelet aggregation drugs and thrombolytic drugs. The overall market size of China’s antithrombotic drugs is small, but it rapidly grows in recent years. The market growth rate was consecutively over 20% from 2006 to 2012. The market size of hospital-use antithrombotic drugs reaches CNY 9.92 billion in 2012, with an increase of 21.9% YOY.

As the population further aging in China, on one hand, the incidence rate of vascular embolic diseases rises year by year; on the other hand, surgeries such as the interventional treatment of cardiovascular and cerebrovascular rapidly develop. The synchronous follow-up of anti-freezing, anti-platelet and lowering the blood lipid treatment after the stent surgery, promotes the capacity expansion of China’s antithrombotic drug market. The market size of China’s hospital-use antithrombotic drugs is expected to be over CNY 20 billion in 2017.

Hawa Valves Starts Development of The New Plant in Hubli

Engineers from all over the world keep on doing their research to ensure that they invent new ways to advance technology and make work easier. This is the main reason why industrial apparatus like ball valves and sanitary valves are always being modified and made to be more effective.

A ball valve, one type of quarter turn valve, is quite literally a ball placed in a passageway through which fluid flows. The ball has a hole through it, by which the valve opens and closes. When the ball is positioned so that the hole runs the same direction as the passageway, the fluid simply flows through the hole, and the valve is open. However, when the ball is positioned so that the hole is perpendicular to the passageway, the fluid cannot pass through, and the valve is closed.

A ball valve is usually a kind of disc used in most industries to link up and strengthen joints where they are made to withstand extreme pressures and high temperatures. They are made to withstand temperatures as high as above 200 degrees centigrade without bending or melting. Different manufacturers all over the world make ball valves and each is suited for a particular purpose. They vary in sizes and this means that some valves may be used for bigger industrial applications, while others are good for ordinary industrial use.

All companies that make valves do so by using metal, plastic, or even ceramics to make them. Nevertheless, good valves should be simple and easy to use. They should also be durable, and where possible easy to replace in case they get some technical malfunctioning. A good ball valve should offer the most resistance between the disc and the sleeve regardless of whether the liquids or gases inside the tubes are extremely compressed.

There are three different types of ball valve. A full port ball valve offers no flow restriction, which means that when the ball valve is open, the liquid can flow freely through it. This is achieved by making the ball larger than the passage size, so that the hole bored through it can be the same size as the passage. A standard port ball valve does not have an oversized ball, and as a result the hole is one size smaller than the passageway.

India is among the emerging industrial apparatus-manufacturing giants, and a ball valve India is an example of how technology here is advancing. Ball valves India are used in industries such as food industries, beverage-making industries and even in other complex industries like nuclear and atomic industries. The advantage of ball valves India is that they are cheap, and are always tested rigorously before being sold to industries to ensure that they can perform effectively.

Conducting Research Through Cognitive Laboratories

Johnson and Duran encouraged use of cognitive laboratories as a means for determining whether lack of access skills impede measurement of target skills. With cognitive laboratories, students work one-on-one with an administrator and answer test questions by thinking out loud. The administrator observes and records the thought process students use in arriving at their answers.

Cognitive labs would allow researchers to compare how students with various disabilities react to the questions under different accommodations and to do further study into what constituted appropriate accommodations. Further Research on the Performance of English-Language Learners Duran commented that better understanding of the achievement of English-language learners depends on improvements in access to appropriate assessment accommodations for these students. He called for additional work to develop ways to evaluate the English proficiency of nonnative English speakers. This is a particularly urgent issue in light of the recently passed legislation. He also encouraged researchers to examine the relationships between performance of achievement tests and relevant background variables, such as length of residence in the U.S., years of exposure to instruction in English, English-language proficiency levels, the characteristics of school curriculum, availability of first and second language resources, and other factors that interact to create different patterns of performance on assessments.

Malouf raised questions about what rate of participation should be expected with NAEP The presentations and his own examination ofNAEP publications indicate that inclusion rates rarely climb much above 70 percent of the students with disabilities and are usually lower. He wondered what the basis might be for judging whether this rate of inclusion was high enough, asking “Should our expectations be based on technical limits, or should they be based on other considerations?” iMaloufcalled for reconsideration of what it means to “rake part meaningfully” in the nation’seducational system, and he urged NAEP’s sponsors to determine ways that all students can participate.

The discussants revisited the issue of providing disaggregated results. Goertz reminded participants that states are required to report these comparisons on their state tests. NAEP’s sponsors have yet to specify their plans for using data from the national or state NAEP programs to report on the performance of students with disabilities compared to that of nondisabled students and the performance of English-language learners compared to that of native speakers. Johnson maintained that it is inevitable that there will be strong pressure on NAEP to report disaggregated results for students with disabilities and for English-language learners. For this part, learning a foreign language needs a leaning tools, many children choose Rosetta Stone Polish and Rosetta Stone Portuguese to learn Polish and Portuguese. Although at this time sample sizes are not large enough to allow reliable reporting at the disaggregated level, NAEP’s future plans for combining state and national samples may produce large enough samples to allow for disaggregation of various groups of students with disabilities. Johnson foresees that when this happens, NAEP will not be able to withstand the pressure to report disaggregated results.

Additional Research Is Needed Malouf also recommended the effects of accommodations that additional research be conducted on on NAEP scores. (item response theory) and DIF (differential item He finds that the IRT i functioning) analyses discussed by Mazzeo are broad in Focus and treat accommodations as single factor, sometimes even combining students with disabilities and English-language learners into a single population. Malouf suggested that NAEP researchers find ways to increase sample sizes to allow study of the effects of specific accommodations and to conduct more fine-grained analyses of accommodations and NAEP.

RMS Titanic

The overwhelming story of Titanic would never be forgotten as it has created the history. It is termed as a greatest marvel which human hands could create possibly. The term RMS stands for Royal Mail Ship, a biggest and the greatest vessel built in its time ever. Titanic was not just a ship it was much more than it; gigantic size, profound luxury and magnificent speed made it a remarkable creation. White Star Line, a British shipping company was the creator of Titanic. The chairman of this shipping company was Joseph Bruce Ismay. Wolff and Harold shipyard undertook this task under construction in Belfast, Ireland. According to its parent figures, crew members and passengers it was considered as an Indestructible body built with a latest technology, it was also perceived as an unsinkable ship. It made its manufacturers confident and proud about the creation they made, competitors were envied and marvelled by this creation and its popularity across the nation raised a wish to be a passenger on the RMS Titanic.

Latest safety equipment’s and technology was endowed in making of this ship. RMS Titanic was a first ship with a mighty size that gave superior comfort and luxury. To make this ship virtually unsinkable the best combination of engine and technology was used. The configuration and features of this craft which made it superior from other are: It was gigantic vessel with a length of 882 feet 9 inches and 92 feet 6 inches of breadth, 104 feet tall and it weighed 52,310 tons.

RMS Titanic consists of 3 engines, 159 furnaces, 29 boilers and 10 decks. The capacity of its electrical plant was much more than a standard city power station at that time. The ship was completely equipped with essential facilities such as wireless telegraph system, waterworks, and insulated ducts to convey warm air throughout; electric heaters were fitted in first class cabins. The luxury and comfort was speechless; Variety of facilities like an electric bath, a gymnasium a swimming a verandah cafe etc. was offered to the first class passengers.

This ship carried 3,339 people which consist of three classes. Passengers were provided with facility of newspapers which was published by Atlantic Daily Bulletin which contained latest news which was received using the wireless telegraph on the ship. The Grand Stairway was its prime attraction. Titanic movie reveals the whole story of RMS titanic which was released in the year 1997.

In spite of all the essential features the marvellous titanic now lies in the depth of the Atlantic Ocean. This sinking craft claimed some 1,500 lives which included the well renowned personalities.

Clinical Trials Are a Must By The Pharmaceutical Companies For Safety

Everyone is aware of the fact that it is difficult to sustain the pressures of the market and to avoid it; the companies need to know the tactics to deal with it. Certain measures need to be taken to keep up with the speed of innovations being made in the market. By following the best practices made in other successful industries and companies, the companies that are witnessing loss for some varied reason or the other, can now see some hope in being able to get out of the loss that would have taken them from good to bad. There are many industries that have contributed to their most to the market to create standards for the economic structure of the nation. Pharmaceutical industry is one such industry, which would never lay low, since the need for medical devices and drugs would never die, instead would give way to the improved version of them all, which could prove more fruitful for the patients and help in faster recovery.

So as to be beneficial for the patients, pharmaceutical companies discover newer methods to treat the needy. For innovations to prove beneficial to the general public clinical studies plays a vital role in educating the officials of the pharmaceutical industry. To develop varied drugs that could prove useful to the mass clinical trials need to take place, and these clinical trials are crucial to the effective research and development of products, medicines and tools that are essential for the healthcare industry and research, as, only after the trials being conducted the officials of this particular field would know about the advantages and disadvantages of the products, so that if any glitches found it can further be rectified.

There are some things that pharmaceutical and medical companies need to be aware of when performing clinical trials, as conducting trials is not an easy task, as it can prove dangerous if not developed on right conditions. Understanding the best practices of this field can increase the functionality and quality of service that these companies offer to the patients. It can so happen many a times, that, if the clinical trials are not conducted and directly the drugs and medical devises are sent to medical stores and if patients happen to buy them and discover the potentiality of the devices and the drugs effect on their body, it would not just prove fatal for the medical store, it may even affect the reputation of the company producing it. Therefore, clinical studies are a necessity before confirming the drugs or devices being approved of safety, and further being sent to varied destinations from where it can be availed by the public easily, and can either use it with their own risk or under the strict supervision of doctors.

Complete Security Only Through a Good Identification System

Security has become a prime issue in almost all places where access has to be controlled. Even in places like schools and colleges only legitimate children have to be allowed entry or say in the Metro, only passengers that have paid the fare and have a valid token or Mifare card can travel. Most schools and even business organizations have an identification system in place so that only legitimate persons are allowed entry.

Salient points of an identification system

An Identification systemhas to consider all the administrative and logistics issues that are relevant to the organization and the site that has to be secured. Due consideration has to be given to the number of people to be issued an ID card and the necessary information about each person has to be stored in a database. If photo identity is required then facility to take the photograph and storing a copy is required. An ID printing process has to be established with the card printer having the required features. This printer has to be put to use at the point of issue of the ID cards.

Some places like the hospital buildings or airport terminals require different levels of security for different areas. For example visitors can enter only specific areas during specific timings in an hospital. Only doctors and nursing staff can enter operation theaters or intensive care units. For the ease of scrutiny the identification system in a hospital can issue color coded ID badges to patients, visitors and hospital staff.

Data regarding how many ID cards are issued and of what type, to whom and when each ID card was issued, for visitors or temporary cards, how many were issued and how many returned, lost cards etc has to be carefully maintained to find breach in security if any or to take measures to improve security of the place.

Main components of an identification system

The main parts of an identification system are the following:

1. The database that stores all the information regarding the card holders, cards issued, types of cards, lost cards, cards in stock etc.

2. The ID cards printer that can access information from the database and print the card with requisite security measures.

3. Accessories like the digital camera to take photographs of card holders and are accessed by the printer when the ID cards are printed.

4. Color coded lanyards or badge holders and the issuance of these.

5. Trained personnel for verification of ID cards at the points of entry, exit and sometimes in between as required.

6. Regular examination of reports and physical verification of stocks of cards in hand. 7. Improvements and changes in the identification system after regular study. Thus it is the complete identification system that is responsible for the security of places and organizations and due importance should be given to see that it is fool-proof.

College Students Still Power BitTorrent Users

Though ISPs and the entertainment industry have teamed up to continue to fight the battle against illegal file sharing, college students remain unphased and are still BitTorrent superusers. The rising cost of tuition combined with the widespread availability of Wi-Fi and internet on college campuses could be contributing to the heavy number of BitTorrent users found in colleges across the U.S., though evolving technologies and tech savviness are also likely contributing to the steady use of BitTorrent technology amongst college students.

Since the days of Napster, college students have been some of the most frequent and heaviest file sharers. However, BitTorrent technology is much more complex than the peer-to-peer sharing that took place before heavier government enforcement on file sharing came about. The other difference with BitTorrent is that students can share more than just music – they can also share movies, TV shows, as well as expensive software. When looked at in this way, it makes sense that college students would be the ones getting the most benefit out of file sharing services.

Though many mistake the use of BitTorrent with illegal file sharing, it is not always so. BitTorrent technology can be used to transmit content legally, though it has caught a bad reputation as a tool used for illegal online activity. In 2010, the issue of illegal file sharing became such a problem for the government that they threatened to cut funding to schools that refused to discipline students who were found to be illegally sharing content via BitTorrent or other cloud-based file sharing services.

TorrentFreak, a company that tracks IP addresses and content shared via BitTorrent technology found that today’s university students are using the technology mostly to download entertainment related files such as feature films, video games, and music. However, they also found that Microsoft Office for Mac and other Microsoft Office products were among some of the most heavily downloaded files. Downloading these files saves students the $120 fee that Microsoft charges students for their programs. Thus in the case of software it’s likely more about students being strapped for cash than anything else.

Many of the top BitTorrent using schools are large universities that have economically diverse student populations and where simply more students attend, which increases the amount of BitTorrent hits per month. Even though BitTorrent use has not seen a decline at the university level, is it all such a bad thing?

The cost of college continues to rise as does the need for a college degree in order for young adults to find employment, so is it right that schools require specific programs that students have to pay additional monies in order to acquire? Students also need down time and if they choose to see a movie or play a video game, then rather than shell out the high costs of entertainment activities they are likely going to download it for free. If the entertainment and software industries want less students to download content illegally, then they need to work towards meeting the consumer demand of alternative, less expensive products.

Cell Phone Lookup Services Online

Cell phone lookup services may seem to be ordinary, but they can make a huge difference in certain situations. They have many advantages which include making it very easy to search for someone’s phone number. Simply type a name and you can find the number in a matter of few moments. Until a few years ago, this facility was only available offline. The process of searching for a number was tedious and time consuming. It required looking up the directory and searching for the number or name. This online phone number lookup service is extremely quick and the search results are displayed almost immediately.

Here are some benefits of this service.

Benefits of Cell Phone Lookup

Search public records: This facility helps you to look up for public records, criminal records, property records, and so on. You can find all types of numbers under one roof. Whether it is an industry specific number lookup or general public records, you can find these all on this portal.

Background checks: Employers can benefit a great deal from these services. They can conduct background checks for candidates without having to hire a third party service provider for such verification. This service not only saves cost, it also saves time since there is no need for interaction and coordination with a third party service provider.

Reverse cell phone lookup: Do you receive calls from unknown numbers? If yes, this service will help you find not only the phone number, but also the owner’s name and address. You can reverse look up cell phone numbers, landline numbers, business phone numbers, pager numbers, toll-free phone numbers, and private and unpublished phone numbers. Simply enter one phone number in the search engine and you will get information like full name, current address, phone number history, and billing information. Moreover, once you get the records of someone, you can cross search the number against public records, criminal records, property records, and the like.

Advance searches: The cell phone lookup service also offers some advance searches like background checks, relatives and neighbors’ data, and a full phone report. Typically, the full report would include the name of the cell phone owner, phone’s location, phone company, phone carrier, and line type. It will also include the owner’s address.

Apart from these benefits, you can be assured that your searches are confidential. When you search for numbers, your information will not be shared with third parties. Moreover, you can search for unlimited records if you take up a yearly membership. In fact, you can also opt for a monthly phone number lookup service.

The reverse cell phone lookup service will also help you fight back against telemarketers. If you have added your name to the Do Not Call list and you are still receiving calls from unknown numbers, you can trace the company or the caller to initiate further action. You can follow a correct procedure to stop this kind of disturbance. You will have access to all the information that you need to initiate a procedure.

Pieces Of New Dinosaur Match Together By A Puzzler Genius

At we are always fairly proud to promote the merit of jigsaw puzzle building. In fact the enthusiast puzzler appear to develop a lot of abilities and right now we wish to discuss about a jigsaw puzzle enthusiast, Ian Morrison, who managed to have a dinosaur called after him. How did that come about you may wonder? Well, the Royal Ontario Museum, Canada, had been keeping in its drawers for about half a century 3 pieces of dinosaur jawbone fossils without being in a position to put them with each other in a way that would make sense. The pieces were found in Alberta in 1950. Despite David Evans, palaeontologist and head of the ROM’s dinosaur research division, along with a colleague having spent on and off a lot of time over the last six to 8 years they nevertheless couldn’t determine how the fragments could fit.

At that point David Evans and his team decided to call for assistance Ian Morrison who had been a technician for the ROM for about twenty two years and was known for his abilities at solving jigsaw puzzles. Getting a whole new stand at the challenge it took just 10 minutes for Ian Morrison to get these three fragments with each other in a way that made sense and to the great surprise and satisfaction of everyone. It turned out that that beaked dinosaur was an not known species from the leptoceratopsid kind. The herbivore dinosaur is about the size of a big dog and is horned. Evans and his staff named the dinosaur Gryphoceratops morrisoni: in relation to Gryphon the mythical part lion part eagle mythic animal and morrisoni the Latinized name of the blissfully skilled technician.

The Gryphoceratops morrisoni is the oldest one and also the smallest of all the known leptoceratopsids and is thought to be 84 million years old according to the dating of a stone he was discovered under. That is yet another instance proving how in many various fields jigsaw puzzle solving skills can assist. Jigsaw puzzles were in reality conceived in the end of the 18th century, in 1797 for being more accurate, by the Englishman John Spilsbury who took a map of the world on a piece of wood and cut out each and every country to make a tutorial tool to aid kids to study geography. So Jigsaw puzzles leave high to their virtuous tradition and from the instance mentioned before it seems that puzzle solving allowed research to move ahead and we are rather glad about it.

At we are proud with our great selection of jigsaw puzzles we now have gathered for yourself to purchase on-line and we wish to offer you to pay a visit to our Educational area where you can see in how various means you could use jigsaw puzzles to teach your kids with numbers, letters or geography to name a few. Oh, and naturally we have a great number of jigsaw puzzles regarding dinosaurs so definitely we imagine you ought to browse our site. We hope you enjoyed reading that article. We are at all times happy to share our passion for jigsaw puzzles as we just really like them, all of them and they come in many sizes, kinds and colours and so whatever your inclinations are we should have a jigsaw puzzle for you to buy on the web. Should you have any question make sure you feel free to contact us.

Do You Know About Sea Spider

Introduction to Sea Spiders

Sea spider is also known as Pantopoda or Pycnogonida. The scientific name of Sea spider is Callipallene brevirostris. It is a common and widespread species found in the Mediterranean and Caribbean seas as well as the Artic and Antarctic Oceans. The size ranges from 1 to 10 millimeters to over 90 centimeters. There are around 1300 known species of sea spiders. They have long legs in contrast to the size of the body. The number of walking legs is four pairs, but spiders with five pairs and six pairs exist. They are a member of Phylum Arthropoda. Sexes are separate and males and females cling together for the process of reproduction. The average life span is around one year.

Information about its biology, habitat and types of Sea Spider

Biology They have a small and slender body. They have no respiratory and excretory system. They release gases by diffusion. Food is externally digested in most species. Sea spider has two, three or four simple eyes on the top of its head. They have three pairs of appendages known as chelicerae, which are utilized for grasping food.

Metabolic wastes are lost through the digestive tract while other wastes are stored in the cuticle and released during moult. Sea spiders have a circulatory system and a nervous system. The branches of reproductive and digestive systems reach up to legs. Classification of this group depends on the presence or absence of anterior appendages. They look like under fed spiders .Their body is reduced and only a small place is left for the legs to be attached.

Abdomen is smaller than cephalothoraxes or proboscis. The shape and size of proboscis is variable between species. Females lay eggs on the egg-carrying legs of the male. They carry the eggs until they hatch.


They are found in different parts of the world. They are common in shallow waters, but can be found as deep as 7, 000 meters and live in both marine and estuarine habitats. They migrate to sub littoral zones during winter season. They walk along the floor with their stilt-like legs or swim by pulsing them in motion. Most are carnivores and feed on Cnidarians, sponges, polychaetes and bryozoans. The sea spider also feeds on marine worms, sea anemone.


They are generally predators or scavengers. Pycnogonids are predators that feed by sucking the bodily fluids from other marine animals. They are common in tide pools, but these intertidal species are typically small and hard to see, whereas deep sea pycnogonids can grow up to 50 cm. They spend most of their time on seafloor. They are completely unrelated to the terrestrial spiders but superficially resemble them. This species are found on the underneath stones and sea weeds. It is able to swim and also lives in shallow water.

Sea Giant Spider

The scientific name of deep sea giant spider is Colossendies. It is found in the East Pacific region at about 2.5 km depth. They feed on corals, sessile organisms, sucking up their contents through their enormous proboscis. Males take care of the eggs and young ones.